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Antisoma focuses its activities on treatments for cancer, an area of significant unmet medical need.

Antisoma has a diverse portfolio of products in development. Our products target tumours by several different mechanisms and are intended for the treatment of a range of cancers.

ASA404 (DMXAA, formerly AS1404)


A first-in-class Tumour-Vascular Disrupting Agent (Tumour-VDA) in trials for various solid tumours and entering phase III in non-small cell lung cancer.

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AS1413 (amonafide malate, formerly XanafideŽ)

AS1413, formerly XanafideŽ, is a DNA intercalator in phase III development in secondary AML.

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AS1411


A DNA aptamer in phase II in acute myeloid leukaemia (AML).

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Oral fludarabine


Oral fludarabine is a nucleoside analogue in registration for CLL.

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AS1402 (huHMFG1)


A humanised monoclonal antibody against MUC1 being prepared for a phase II trial in breast cancer.

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AS1409 (huBC1-huIL12)


An antibody-cytokine fusion protein for targeted delivery of IL-12 currently in phase I in renal cell carcinoma and melanoma.

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P2045


P2045 is a synthetic peptide-based targeted radiopharmaceutical in phase I studies.

Pipeline highlight




View our product pipeline
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